The Sign of Four: Sherlock Holmes' Greatest Case (1932) is a Mystery, Thriller, Romance, Crime, Action film that follows a young woman turns to Holmes for protection when she's menaced by an escaped killer seeking missing treasure. However, when the woman is kidnapped, Holmes and Watson must penetrate the city's criminal underworld to find her. Currently, you can watch The Sign of Four: Sherlock Holmes' Greatest Case on Amazon Video. Streaming availability may vary by country and platform over time. It has a user rating of 4.8 out of 10 from 15 votes. Fans of mystery movies may also want to explore similar titles below.